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isoniazid will raise the stage or result of pazopanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Avoid coadministration of pazopanib with sturdy CYP3A4 inhibitors if at all possible; if will have to coadminister, reduce pazopanib dose to four hundred mg/working dayexpression in gastric most cancers cells. A